Monday, July 15, 2013

Side effects vs. serious side effects

Peripheral neuropathy is a disconcerting and some what debilitating side effect of some of my chemotherapy drugs. There is a medicine you can take and it may alleviate symptoms. It does not work instantly; you start off with 1 pill three times a day and increase dosage until you experience relief or you reach the maximum recommended dosage of 3 pills 3 times a day.
Side effects may include suicidal tendencies, lack of dancing ability, and swelling in the extremities.
Originally designed as an anti-epilepsy drug, it targets the firing of the synapses. This has the potential of fundamentally changing the chemical structure of my nervous system.  The chemotherapy soup in my blood has already made adverse changes to my body; like neuropathy.
The risk management perspective says: “high risk of serious side effects, low probability any benefit (1/3 of patients taking it for neuropathic pain reported relief).” Additional risks with this drug include the quitting process. Since you have to build up a certain concentration before the drugs is effective means you are somewhat saturated. The withdrawal, if not done with care, is similar to the DT shakes that alcoholics have when quitting cold turkey and in a few cases has caused epilepsy.

Mind you this is to alleviate the side effects of another drug.

So I started comparing pain I have experienced to the peripheral neuropathy I am experiencing.

1978 Riverside California. Uncle Bob gave me my first skateboard. It was an orange fiberglass beauty shaped kind of like a surfboard. About 3 inches wide, and 7 inches long with functional trucks and urethane wheels. It was absolutely bitchin'.

Paradigm shifts often cause huge changes in technology and tactics. There was no grip tape, roughed up surface, or even surfboard wax to help keep your feet on the board. Dummy was barefoot anyway because surfers didn't wear shoes. Self-taught skateboarders are a different breed. The trail and error method of learning is a tough way to acquire skills. After an incredible trick, which at this point is probably a turn, I took a fall. I discovered that I had impaled a palm frond under my toenail. God designed the palm frond with a spear shape and backward facing barbs so when it got stuck in something it tended to stay. The artist from Molly Hatchet, Conan movies, and weapons designers worldwide have been inspired ever since.

The peripheral neuropathy I have experienced is not as painful is a palm frond under the big toenail. Definitely less intense but of bit longer duration; I wouldn't recommend either to anyone I liked. The palm frond removal process which involved pliers and a young man/boy trying to act tough was more painful than peripheral neuropathy, as experienced by me, so far. It is interesting that the removal process is not seared into my brain with the same depth as the memory of the initial injury. Perhaps it is such a vivid memory because the initial visual image shocked me.

I am reminded when I consider my current experience to be thankful. My feet and hands feel funny and sometimes hurt a lot…I have functional hands and feet. I have a friend who had a traumatic brain injury and is unable to speak or move very much. Pray for Chad. I am very blessed; I will not use the medicine to alleviate the neuropathy. Thank God the symptoms are cyclic rather than constant.

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Tuesday, July 2, 2013

Peripheral neuropathy

Recovery is happening. About two weeks ago my lovely wife was pushing me around in a wheelchair and today I am walking unassisted, praise God. We fill out a form that addresses side effects and pain levels every time we visit the hospital. A few days ago the answer was “everything hurts and nothing works.” As the chemo drugs concentrations change I can discriminate between particular side effects
Like a real word geek I began searching for words that would more accurately describe the pain. Electric shocks that travel from muscle to muscle throbbing, pounding, stinging, burning, and searing describes the background sensation. Movement requires a lot of cognitive effort. My nerve endings fire randomly every now and then. It is somewhat like having a Vegas Elvis take control of your legs. This adds additional challenge for the balance impaired.
Extreme sensitivity to touch is another symptom that one has been present for a while but was overwhelmed by the pain of the Lapatinib rash. Sensory overload can cause system shutdown. Passing out is not the most restful sleep. As my awesome wife continues to love on me I am getting stronger. Now I am able to distinguish between individual symptoms rather than just be overwhelmed. More of my sleep is refreshing.
I want to program my mind into interpreting strong nervous system feedback as uncontrolled power instead of pain. Therapeutic exercise includes horse stance, hanging stance, half moon steps, and plum flower fist. Crushing news paper and then throwing those pieces into the trash can. I am trying to exercise precision with my motor skills.
Video of the day
Word(s) of the day:
Peripheral neuropathy